Fifth person cured of HIV after stem cell transplant: scientists
A man has been cured of HIV after a stem cell transplant performed after several rounds of chemotherapy, German scientists said on Tuesday. A man has been cured of HIV after a stem cell transplant performed after seve...
Updated: 39 months ago2 min read
A man has been cured of HIV after a stem cell transplant performed after several rounds of chemotherapy, German scientists said on Tuesday.
A man has been cured of HIV after a stem cell transplant performed after several rounds of chemotherapy, German scientists announced on Tuesday. This man would be the fifth known case of someone cured of the virus, The Hill reported. German scientists detailed the case and in 2008 published a study in the journal Nature of a 53-year-old patient diagnosed with HIV. After diagnosis, the patient received
antiretroviral therapy (ART), which is known to suppress viral loads in his body.
Another cured HIV case?
According to media reports, the patient was enrolled in the University Hospital Düsseldorf's IciStem program, known for research into potential anti-HIV drugs that require stem cell transplantation. Three years after diagnosis of HIV infection, the patient also developed symptoms of acute myeloid leukemia. The cancer was in remission with initial chemotherapy but recurred soon after, according to German scientists. In this cancer treatment
, the patient receives a stem cell transplant from a matched donor two years after the cancer diagnosis and five years after the HIV diagnosis.
In addition, the donor had a mutation that would be important for resistance to HIV infection.
Antiretroviral therapy was continued throughout the cancer treatment and the patient's HIV level was lowered and therefore undetectable. In addition, tests were conducted to detect traces of a virus capable of replicating and infecting cells. In 2018, after ten years, the antiretroviral treatment was stopped and he no longer showed any HIV symptoms. These life-saving results were first reported in 2019 by the patient's doctor, Björn-Erik Ole Jensen, reports The Hill.
The first patient to be cured of HIV, named Timothy Ray Brown, received the same type of transplant as a Dusseldorf patient to treat leukemia in 2007. Last year, a woman was also cured of HIV thanks to a cord blood stem cell transplant.

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